High volume disease

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August undefined, 2024

WebNov 19, 2024 · How many patients present with metastatic disease? This high volume/low volume has a certain arbitrariness to it, depending on the imaging you use. Then we have … WebSep 5, 2024 · The CHART trial only recruited patients with high-volume disease on conventional imaging defined as per the CHAARTED study, and did not detail whether patients had de novo or metachronous metastatic disease.

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WebHigh-volume disease was defined as 4 or more bone metastases with 1 or more outside the vertebral bodies or pelvis, or visceral metastases; all other patients were considered to have low-volume disease. WebDec 22, 2024 · Patient is diagnosed with biochemical recurrence of prostate cancer with high-volume castration-sensitive metastatic disease Germline genetic testing is negative Treatment for Recurrence Patient wishes to receive oral treatment with good quality of life so he can continue to be involved in his grandchildren’s activities christmas notes to friends

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WebJan 11, 2024 · High-volume disease per CHAARTED criteria was defined as the presence of visceral metastasis or ≥4 bone lesions with ≥1 beyond the vertebral bodies and pelvis; others were defined as low-volume... WebCHAARTED – there was an implication in the data that suggested that patients with “high volume” disease (visceral metastases or >=4 bone metastases) yielded more benefit than patients with “low volume” disease LATITUDE and STAMPEDE assessed two slightly different cohorts - LATITUDE was limited to cM1 patients (1199 patients included, HR 0.62) WebApr 15, 2024 · Background The long-term excessive intake of exogenous cholesterol can lead to abnormally elevated blood lipid levels and induce cardiovascular and cerebrovascular diseases. However, the influence and relevance of exogenous cholesterol on plasma cholesterol components were still unclear, and the influence on intestinal lipid … getfitinthirty

Hypovolemia: Symptoms, Causes, Diagnosis, and …

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WebIn the first part, abiraterone ranked first for high-volume mHSPC. Conversely, enzalutamide ranked first for low-volume mHSPC. In the second part, abiraterone treatment in high … WebApr 12, 2024 · Docetaxel plus ADT should be offered to patients with metastatic noncastrate prostate cancer with high-volume disease (four or more bone metastases, one or more of which is outside of the spine or pelvis, and/or the presence of any visceral disease) who are candidates for chemotherapy but are unwilling or unable to receive triplet therapy. ... christmas note to friendsWebApr 11, 2024 · Objective: The important effect modifiers of high disease severity on the relationship between the different volumes of early fluid resuscitation and prognosis in septic patients are unknown. Thus, this study was designed to assess whether the efficacy of different volumes in the early fluid resuscitation treatment of sepsis is affected by … get fit lathrop

"WebIn newly diagnosed mHSPC patients, clinicians should assess the extent of metastatic disease (low- versus high-volume). High-volume is defined as greater than or equal to … " - High volume disease

High volume disease

Case 2: High-Volume Versus Low-Volume Metastatic CSPC

WebMar 2, 2024 · Summary of relative and absolute risks for mixed treatment comparisons derived from frequentist network meta-analysis using 4 levels of certainty: high (further research very unlikely to change confidence in the estimate of effect), moderate (further research likely to have important association with confidence in estimate of effect and … WebHigh CCI should alert providers to increased probability of major complications, and warrant vigilant management after CUTE. Surgeon volume was inversely related to major postoperative complications. Perioperative Complications and Mortality in Patients with Urothelial Carcinoma and End-Stage Renal Disease Undergoing One-Stage Complete …

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WebApr 15, 2024 · Background The long-term excessive intake of exogenous cholesterol can lead to abnormally elevated blood lipid levels and induce cardiovascular and … WebA total of 57% of patients had a high metastatic burden and 60% of patients received docetaxel. The median follow-up for the ADT + docetaxel (n = 355) and the ADT + docetaxel + abiraterone (n = 355) was 36 months. The median time to discontinuation of abiraterone in the abiraterone group was 31.4 months.

WebHigh volume disease was defined as the presence of visceral metastases or ≥4 bone lesions with at least 1 lesion beyond the vertebral bodies and pelvis. This study design … WebJul 1, 2024 · Results: The number of patients with CHAARTED low-volume and high-volume diseases was 178 (33.5%) and 354 (66.5%), respectively. On the contrary, the number of patients with LATITUDE low-risk and high-risk diseases …

WebFeb 19, 2024 · Hypovolemia is a loss of more than 15% of the fluid circulating in your body (blood volume). This has many causes, including fluid loss from severe dehydration or … WebJan 31, 2024 · Long-term follow-up of a large phase III study showed that chemohormonal therapy involving docetaxel added to androgen deprivation therapy (ADT) prolongs overall …

WebApr 14, 2024 · Objective Automated brain volumetric analysis based on high-resolution T1-weighted MRI datasets is a frequently used tool in neuroimaging for early detection, diagnosis, and monitoring of various neurological diseases. However, image distortions can corrupt and bias the analysis. The aim of this study was to explore the variability of brain …

WebFeb 25, 2024 · There was a smaller effect on overall survival in patients with high-volume disease, those planned for early docetaxel, and those on antiresorptive bone therapy. These subgroup analyses are limited. The amount of follow-up has been not quite as long. We didn’t have as many deaths for the overall survival cohort. christmas note to neighborWebNov 12, 2024 · Choriocarcinoma syndrome is a rare clinical entity with advanced, high volume choriocarcinomatous tumors and markedly elevated B-hCG (>50,000 IU/L). Recognition is important because the diagnosis of this syndrome identifies poor prognosis without mortality-proven management options. christmas note to kidsWebNov 27, 2024 · Defining Disease Volume in Metastatic Prostate Cancer Nov 26, 2024 Transcript: Noel Clarke, MBBS, FRCS, ChM: From a biological standpoint, it is fascinating … christmas note to my husbandWebApr 12, 2024 · In our post-hoc exploratory analysis of the high-volume disease subgroup (n=487 in the abiraterone acetate plus prednisone and 468 in the placebo group), median overall survival was 49·7 months (95% CI 43·2–55·4) with abiraterone acetate plus prednisone compared with 33·3 months (30·2–36·7) with placebos, with an HR for death … christmas noticeWebSep 2, 2014 · In the 520 patients who had high-extent disease, treatment with ADT plus docetaxel had a median overall survival of 49.2 months versus 32.2 in the ADT-only group — a difference of 17 months. christmas note to daycare teacherWebThe CHAARTED study, which defined high-volume disease as that in which patients have either visceral metastases or 4 or more bone metastases, at least one of which is outside the vertebral column or pelvis, found that patients with high-volume disease have a worse prognosis than those with low-volume disease. christmas notice board decorationWebJul 2, 2024 · The patients with CHAARTED high-volume disease or LATITUDE high-risk disease showed a shorter CRPC-free survival and a shorter OS than those in the … get fit juices and shakes morgantown